Sharma Lab Publications

Selected Publications

Synthesis, characterization, and preclinical validation of a PET radiopharmaceutical for interrogating Aβ (β-amyloid) plaques in Alzheimer's disease
Sundaram GS, Dhavale D, Prior JL, Sivapackiam J, Laforest R, Kotzbauer P, Sharma V.
EJNMMI Res. 2015 Dec;5(1):112. PMID: 26061601
Free PMC article available PMCID: PMC4478171

A Generator-Produced Gallium-68 Radiopharmaceutical for PET Imaging of Myocardial Perfusion
Sharma V, Sivapackiam J, Harpstrite SE, Prior JL, Gu H, Rath NP, Piwnica-Worms D
PLoS One. 2014 Oct 29, 9(10): e109361 PMID: 25353349
Free PMC article available PMCID: PMC4212944

Characterization of a Brain Permeant Fluorescent Molecule and Visualization of Aβ Parenchymal Plaques, Using Real-Time Multiphoton Imaging in Transgenic Mice
Sundaram GS, Garai K, Rath NP, Yan P, Cirrito JR, Cairns NJ, Moo-Lee J, Sharma V
Org Lett. 2014 Jul18;16(14):3640-3 PMID: 25003699

Interrogation of multidrug resistance (MDR1) P-glycoprotein (ABCB1) expression in human pancreatic carcinoma cells: correlation of 99mTc-Sestamibi uptake with western blot analysis
Harpstrite SE, Gu H, Natarajan R, Sharma V
Nuc Med Comm. 2014 Oct;35(10): 1067-70 PMID: 25036383

A New Nucleoside Analogue with Potent Activity against Mutant sr39 Herpes Simplex Virus-1 (HSV-1) Thymidine Kinase (TK)
Sundaram GS, Harpstrite SE, Kao JL, Collins SD, Sharma V
Org Lett. 2012 Jul 20;14(14): 3568-71 PMID: 22765027

Synthesis, molecular structure, and validation of novel metalloprobes for assessment of MDR1 P-glycoprotein-mediated functional transport
Sivapackiam J, Harpstrite SE, Prior JL, Gu H, Rath NP, Sharma V
Dalton Trans. 2010, 39: 5842-5850 PMID: 20505882

Radiopharmaceuticals for assessment of multidrug resistance P-glycoprotein-mediated drug transport activity
Sharma V
Bioconjugate Chem. 2004, 15(6): 1464-1474 PMID: 15546216

Noninvasive imaging of protein-protein interactions in living animals
Luker GD, Sharma V, Pica CM, Dahlheimer JL, Li, W, Ocheskey JA, Ryan CE, Piwnica-Worms H, Piwnica-Worms D
Proc. Natl. Acad. Sci. USA 2002, 99: 6961-6966 PMID: 11997447
Free PMC article available PMCID: PMC124511