Maggi Research Publications

Peer Reviewed Manuscripts

The C. elegans Sequencing Consortium.  1998.  Genome Sequence of the Nematode C. elegans: A Platform for Investigating Biology.  Science.  282:2012-2018.

Maggi, LB, Jr., Sadeghi, H, Weigand, C, Scarim, AL, Heitmeier, MR, and Corbett, JA.  2000.  Anti-inflammatory Actions of 15-d-12,14-prostaglandin J2 and Troglitazone: Evidence for Heat Shock-dependent and -independent Inhibition of Cytokine-induced iNOS Expression.  Diabetes.  49:346-355.

Maggi, LB, Jr., Heitmeier, MR, Scheuner, D, Kaufman RJ, Buller, RML, and Corbett, JA.  2000.  Potential Role of PKR in dsRNA-induced Macrophage Activation.  EMBO J.  19:3630-3638.

International Human Genome Sequencing Consortium.  2001.  Initial Sequencing and Analysis of the Human Genome.  Nature.  409:860-921.

Blair, LA, Heitmeier, MR, Scarim, AL, Maggi, LB, Jr., and Corbett, JA.  2001.  Double-stranded RNA-dependent Protein Kinase is Not Required for Double-stranded RNA-induced Nitric Oxide Synthase Expression or Nuclear Factor-B Activation by Islets.  Diabetes.  50:283-290.

Blair, LA, Maggi, LB, Jr., Scarim, AL, and Corbett, JA.  2002.  Role of Interferon Regulatory Factor-1 in iNOS expression by Mouse Islets.  J. Biol. Chem.  277:359-365.
Maggi, LB, Jr., Moran, JM, Scarim, AL, Ford, DA, Yoon, YW, McHowat J, Buller, RML and Corbett, JA.  2002.  Novel Role for Calcium-independent Phospholipase A2 in the Macrophage Antiviral Response of Inducible Nitric-oxide Synthase Expression.  J. Biol. Chem.  277:38449-38455.

Steer, SA, Moran, JM, Maggi, LB, Jr., Buller, RML, Perlman, H, Corbett, JA.  2003.  Regulation of cyclooxygenase-2 expression by macrophages in response to double-stranded RNA and viral infection.  J. Immunol.  170:1070-1076.

Maggi, LB, Jr., Moran, JM, Buller, RML, and Corbett, JA.  2003.  ERK Activation is Required for dsRNA- and Virus-induced IL-1 Expression by Macrophages.  J. Biol. Chem.  278:16683-16689.

Brady, SN, Yu, Y, Maggi, LB, Jr., Weber, JD.  2004.  ARF Impedes NPM/B23 Shuttling in an Mdm2-Sensitive Tumor Suppressor Pathway.  Mol. Cell. Biol. 24:9327-9338.

Kohr, B, Bredemeyer, AL, Huang, CY, Turnbull, I, Evans, R, Maggi, LB, Jr., White, JM, Walker, LM, Carnes, K, Hess, R, and Sleckman, BP.  2006.  Proteasome Activator PA200 Causes Defective Spermatogenesis.  Mol. Cell. Biol. 26:2999-3007.

Yu, Y, Maggi, LB, Jr., Brady, SN, Apicelli, AJ, Dai, MS, Lu, H, and Weber, JD.  2006.  Nucleophosmin is Essential for Ribosomal L5 Nuclear Export.  Mol. Cell. Biol.  26:3798-3809.

Steer, SA, Moran, JM, Christmann, BS, Maggi, LB, Jr., and Corbett, JA.  2006.  Role of MAPK in the regulation of dsRNA and EMCV-induced COX-2 expression by macrophages. J. Immunol. 177:3413-3420.
Pelletier, CP, Maggi, LB, Jr., Brady, SN, Scheidenhelm, DK, Gutmann, DH, and Weber, JD.  2007.  mTOR/S6K1 Sets the Rate of Ribosome Export through Increased Nucleophosmin Translation and Stability. Cancer Res. 67:1200-1209.

Apicelli AJ, Maggi, LB, Jr, Hirbe AC, Miceli, AP, Olanich, M, Schulte-Winkeler, CL, Saporita, AJ, Kuchenreuther, M, Sanchez J. Weilbaecher K.N. and Weber J.D.  2007. A non-tumor suppressor role for basal p19ARF in maintaining nucleolar structure and function.  Mol. Cell. Biol. 28:1068-1080.

Maggi, LB, Jr., Kuchenreuther, M, Schwope, RM, Grisendi, S, Pandolfi, PP, and Weber, JD.  2008.  Nucleophosmin Serves as a Rate-Limiting Nuclear Export Chaperone for the Mammalian Ribosome.  Mol. Cell. Biol., 28:7050-65.

Vanderwaal, RP, Maggi, LB, Jr., Weber, JD, Hunt, CR, and Roti Roti, JL.  2009.  Nucleophosmin Redistribution following Heat Shock: A Role in Heat-Induced Radiosensitization.  Cancer Res., 69:3209-20.

Maggi, LB Jr., Brady, SN, Winkeler CL, Toso EA, Gwinn AS, Pelletier, CL, and Weber, JD.  2009.  Nucleophosmin protein expression level, but not threonine 198 phosphorylation, is essential in growth and proliferation.  Oncogene, 28:3209-20.

Chu, L, Su, MY, Maggi, LB Jr., Lu, L, Mullins, C, Crosby, S, Huang, G, Chng, WJ, Vij, R, and Tomasson, MH. 2012. Chromosomal translocation t(4;14) in multiple myeloma activates ACA11, an orphan snoRNA within WHSC1, to modulate oxidative stress. J. Clin. Inv. 122:2793-2806.

Winkeler, CL, Kladney, RD, Maggi, LB, Jr., and Weber, JD.  2012.  Cathepsin K-Cre Causes Unexpected Germline Deletion of Genes in Mice.  PLOS One.  7:e42005

Chang, C-H, Curtis, JD, Maggi, LB, Jr., Faubert, B, Villarino, AV, O’Sullivan, D, Huang, SC-C, van der Windt, GJW, Blagih, J, Qui, J, Weber, JD, Pearce, EJ, Jones, RG, and Pearce, EL.  2013.  Post-Transcriptional Control of T Cell Effector Function by Warburg Metabolism. Cell. 153:1239-1251.

Forys, JT, Kuzmicki, CE, Saporita, JA, Winkeler, CL, Maggi, LB Jr., and Weber, JD.  2014. ARF and p53 coordinate tumor suppression of an oncogenic IFN--STAT1-ISG15 signaling axis.  Cell Rep. 7:514-526.

Invited Reviews

Maggi, LB, Jr., and Weber, JD.  Nucleolar Adaptation in Human Cancer.  2005.  Cancer Invest.  23:599-608.

Saporita, AJ, Maggi, LB, Jr., Apicelli, AJ, and Weber, JD.  2007.  Therapeutic Targets in the ARF Tumor Suppressor Pathway. Curr. Med. Chem. 14:1815-1827.

Maggi, LB, Jr., and Weber, JD.  2013.  Forget Transcription: Translation is Where the Action Is.  Mol. Cell. Biol.  33:1884-1885.

Maggi LB Jr., Winkeler CL, Miceli AP, Apicelli AJ, Brady SN, Kuchenreuther MJ, and Weber JD.  2014.  ARF Tumor Suppression in the Nucleolus.  Biochim Biophys Acta. 1842:831-839.