Maggi Research Publications

Peer Reviewed Manuscripts

The C. elegans Sequencing Consortium.  1998.  Genome Sequence of the Nematode C. elegans: A Platform for Investigating Biology.  Science.  282:2012-2018.
http://www.sciencemag.org/content/282/5396/2012

Maggi, LB, Jr., Sadeghi, H, Weigand, C, Scarim, AL, Heitmeier, MR, and Corbett, JA.  2000.  Anti-inflammatory Actions of 15-d-12,14-prostaglandin J2 and Troglitazone: Evidence for Heat Shock-dependent and -independent Inhibition of Cytokine-induced iNOS Expression.  Diabetes.  49:346-355.
http://diabetes.diabetesjournals.org/content/49/3/346

Maggi, LB, Jr., Heitmeier, MR, Scheuner, D, Kaufman RJ, Buller, RML, and Corbett, JA.  2000.  Potential Role of PKR in dsRNA-induced Macrophage Activation.  EMBO J.  19:3630-3638.
http://emboj.embopress.org/content/19/14/3630

International Human Genome Sequencing Consortium.  2001.  Initial Sequencing and Analysis of the Human Genome.  Nature.  409:860-921.
http://www.nature.com/nature/journal/v409/n6822/abs/409860a0.html

Blair, LA, Heitmeier, MR, Scarim, AL, Maggi, LB, Jr., and Corbett, JA.  2001.  Double-stranded RNA-dependent Protein Kinase is Not Required for Double-stranded RNA-induced Nitric Oxide Synthase Expression or Nuclear Factor-B Activation by Islets.  Diabetes.  50:283-290.
http://diabetes.diabetesjournals.org/content/50/2/283

Blair, LA, Maggi, LB, Jr., Scarim, AL, and Corbett, JA.  2002.  Role of Interferon Regulatory Factor-1 in iNOS expression by Mouse Islets.  J. Biol. Chem.  277:359-365.
http://www.jbc.org/content/277/1/359
 
Maggi, LB, Jr., Moran, JM, Scarim, AL, Ford, DA, Yoon, YW, McHowat J, Buller, RML and Corbett, JA.  2002.  Novel Role for Calcium-independent Phospholipase A2 in the Macrophage Antiviral Response of Inducible Nitric-oxide Synthase Expression.  J. Biol. Chem.  277:38449-38455.
http://www.jbc.org/content/277/41/38449

Steer, SA, Moran, JM, Maggi, LB, Jr., Buller, RML, Perlman, H, Corbett, JA.  2003.  Regulation of cyclooxygenase-2 expression by macrophages in response to double-stranded RNA and viral infection.  J. Immunol.  170:1070-1076.
http://www.jimmunol.org/content/170/2/1070

Maggi, LB, Jr., Moran, JM, Buller, RML, and Corbett, JA.  2003.  ERK Activation is Required for dsRNA- and Virus-induced IL-1 Expression by Macrophages.  J. Biol. Chem.  278:16683-16689.
http://www.jbc.org/content/278/19/16683

Brady, SN, Yu, Y, Maggi, LB, Jr., Weber, JD.  2004.  ARF Impedes NPM/B23 Shuttling in an Mdm2-Sensitive Tumor Suppressor Pathway.  Mol. Cell. Biol. 24:9327-9338.
http://mcb.asm.org/content/24/21/9327.long

Kohr, B, Bredemeyer, AL, Huang, CY, Turnbull, I, Evans, R, Maggi, LB, Jr., White, JM, Walker, LM, Carnes, K, Hess, R, and Sleckman, BP.  2006.  Proteasome Activator PA200 Causes Defective Spermatogenesis.  Mol. Cell. Biol. 26:2999-3007.
http://mcb.asm.org/content/26/8/2999

Yu, Y, Maggi, LB, Jr., Brady, SN, Apicelli, AJ, Dai, MS, Lu, H, and Weber, JD.  2006.  Nucleophosmin is Essential for Ribosomal L5 Nuclear Export.  Mol. Cell. Biol.  26:3798-3809.
http://mcb.asm.org/content/26/10/3798.long

Steer, SA, Moran, JM, Christmann, BS, Maggi, LB, Jr., and Corbett, JA.  2006.  Role of MAPK in the regulation of dsRNA and EMCV-induced COX-2 expression by macrophages. J. Immunol. 177:3413-3420.
http://www.jimmunol.org/content/177/5/3413
 
Pelletier, CP, Maggi, LB, Jr., Brady, SN, Scheidenhelm, DK, Gutmann, DH, and Weber, JD.  2007.  mTOR/S6K1 Sets the Rate of Ribosome Export through Increased Nucleophosmin Translation and Stability. Cancer Res. 67:1200-1209.
http://cancerres.aacrjournals.org/content/67/4/1609.long

Apicelli AJ, Maggi, LB, Jr, Hirbe AC, Miceli, AP, Olanich, M, Schulte-Winkeler, CL, Saporita, AJ, Kuchenreuther, M, Sanchez J. Weilbaecher K.N. and Weber J.D.  2007. A non-tumor suppressor role for basal p19ARF in maintaining nucleolar structure and function.  Mol. Cell. Biol. 28:1068-1080.
http://mcb.asm.org/content/28/3/1068.long

Maggi, LB, Jr., Kuchenreuther, M, Schwope, RM, Grisendi, S, Pandolfi, PP, and Weber, JD.  2008.  Nucleophosmin Serves as a Rate-Limiting Nuclear Export Chaperone for the Mammalian Ribosome.  Mol. Cell. Biol., 28:7050-65.
http://mcb.asm.org/content/28/23/7050.long

Vanderwaal, RP, Maggi, LB, Jr., Weber, JD, Hunt, CR, and Roti Roti, JL.  2009.  Nucleophosmin Redistribution following Heat Shock: A Role in Heat-Induced Radiosensitization.  Cancer Res., 69:3209-20.
http://cancerres.aacrjournals.org/content/69/16/6454.long

Maggi, LB Jr., Brady, SN, Winkeler CL, Toso EA, Gwinn AS, Pelletier, CL, and Weber, JD.  2009.  Nucleophosmin protein expression level, but not threonine 198 phosphorylation, is essential in growth and proliferation.  Oncogene, 28:3209-20.
http://www.nature.com/onc/journal/v28/n36/full/onc2009178a.html

Chu, L, Su, MY, Maggi, LB Jr., Lu, L, Mullins, C, Crosby, S, Huang, G, Chng, WJ, Vij, R, and Tomasson, MH. 2012. Chromosomal translocation t(4;14) in multiple myeloma activates ACA11, an orphan snoRNA within WHSC1, to modulate oxidative stress. J. Clin. Inv. 122:2793-2806.
http://www.jci.org/articles/view/63051

Winkeler, CL, Kladney, RD, Maggi, LB, Jr., and Weber, JD.  2012.  Cathepsin K-Cre Causes Unexpected Germline Deletion of Genes in Mice.  PLOS One.  7:e42005
http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0042005

Chang, C-H, Curtis, JD, Maggi, LB, Jr., Faubert, B, Villarino, AV, O’Sullivan, D, Huang, SC-C, van der Windt, GJW, Blagih, J, Qui, J, Weber, JD, Pearce, EJ, Jones, RG, and Pearce, EL.  2013.  Post-Transcriptional Control of T Cell Effector Function by Warburg Metabolism. Cell. 153:1239-1251.
http://www.sciencedirect.com/science/article/pii/S0092867413005825

Forys, JT, Kuzmicki, CE, Saporita, JA, Winkeler, CL, Maggi, LB Jr., and Weber, JD.  2014. ARF and p53 coordinate tumor suppression of an oncogenic IFN--STAT1-ISG15 signaling axis.  Cell Rep. 7:514-526.
http://www.sciencedirect.com/science/article/pii/S2211124714002046

Invited Reviews

Maggi, LB, Jr., and Weber, JD.  Nucleolar Adaptation in Human Cancer.  2005.  Cancer Invest.  23:599-608.
http://informahealthcare.com/doi/abs/10.1080/07357900500283085

Saporita, AJ, Maggi, LB, Jr., Apicelli, AJ, and Weber, JD.  2007.  Therapeutic Targets in the ARF Tumor Suppressor Pathway. Curr. Med. Chem. 14:1815-1827.
http://www.eurekaselect.com/59506/article

Maggi, LB, Jr., and Weber, JD.  2013.  Forget Transcription: Translation is Where the Action Is.  Mol. Cell. Biol.  33:1884-1885.
http://mcb.asm.org/content/33/10/1884.long

Maggi LB Jr., Winkeler CL, Miceli AP, Apicelli AJ, Brady SN, Kuchenreuther MJ, and Weber JD.  2014.  ARF Tumor Suppression in the Nucleolus.  Biochim Biophys Acta. 1842:831-839.
http://www.sciencedirect.com/science/article/pii/S0925443914000325